




Socio-Economic
and
Other
Correlates
of
KaposiSarcoma-Associated
Herpesvirus
SeroprevalenceAmong
Older
Adults
in
SicilyColleen
Pelser,1,2
Francesco
Vitale,3
Denise
Whitby,4
Barry
I.
Graubard,1
Angelo
Messina,5Lorenzo
Gafa`
,6
Elizabeth
E.
Brown,7
Lesley
A.
Anderson,1,8
Nino
Romano,3Carmela
Lauria,6
and
James
J.
Goedert1*1Division
of
Cancer
Epidemiology
&
Genetics,
National
Cancer
Institute,
National
Institutes
of
Health,Rockville,
MarylandThe
virus
that
causes
Kaposi
sarcoma,
KSassociated
herpesvirus
(KSHV,
also
knownas
human
herpesvirus
8)
has
an
unusual
distribution
and
poorly
characterized
modes
oftransmission.
To
clarify
these
issues,
sociodemographic
correlates
of
KSHV
seroprevalencewere
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BRIEF
COMMUNICATIONRisk
of
Classic
Kaposi
Sarcoma
with
Residential
Exposureto
Volcanic
and
Related
Soils
in
SicilyCOLLEEN
PELSER,
CARMELO
DAZZI,
BARRY
I.
GRAUBARD,
CARMELA
LAURIA,FRANCESCO
VITALE,
AND
JAMES
J.
GOEDERTPURPOSE:
Before
AIDS,
endemic
(African)
Kaposi
sarcoma
(KS)
was
noted
to
occur
in
volcanic
areasand
was
postulated
to
result
from
dirt
chronically
embedded
in
the
skin
of
the
lower
extremities.
Theprimary
cause
of
all
KS
types
is
KS-associated
herpesvirus
(KSHV)
infection,
but
cofactors
contribute
tothe
neoplasia.
We
investigated
whether
residential
exposure
to
volcanic
or
...continua
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